PROOF-Study: The efficacy and safety of high-dose intravenous fosfomycin (5 g every 8 hours) in combination with other antibiotic is evaluated in complicated bone and implant-associated infections caused by staphylococci, enterococci and gram-negative organisms.
- standard treatment (6-10 weeks until reimplantation)
- "fast-track" treatment (2-3 weeks short interval).
PRO-IMPLANT Foundation is launching the "Homecare" Trial evaluating the feasibility of intravenous treatment at patient home. This study aims to improve quality of life and reduce hospital stay in patients requiring prolonged intravenous antibiotic therapy.